Nocodazole - CISMeF

Preferred Label : Nocodazole;

NCIt synonyms : Methyl (5-(2-thienylcarbonyl))-1H-benzimidazol-2-yl;

NCIt definition : A synthetic tubulin-binding agent with antineoplastic activity. Nocodazole binds to beta-tubulin and disrupts microtubule assembly/disassembly dynamics. This prevents mitosis and induces apoptosis in tumor cells. Although nocodazole binding site overlaps with that of colchicine, the two agents are structurally quite different.;

UNII : SH1WY3R615;

InChIKey : KYRVNWMVYQXFEU-UHFFFAOYSA-N;

CAS number : 31430-18-9; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 31430-18-9 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Chemical formula : C14H11N3O3S;

ChEBI ID : CHEBI:34892;

Details

Origin ID

C75228;

UMLS CUI

C0028247;

Currated CISMeF NLP mapping
- nocodazole [Substance BNPC]
- nocodazole [MeSH Descriptor]
- nocodazole [MeSH concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- nocodazole [Substance BNPC]
- nocodazole [MeSH concept]
- nocodazole [MeSH Descriptor]
chemical_or_drug_has_mechanism_of_action
- Microtubule Process [NCIt concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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