" /> Argatroban Anhydrous - CISMeF





Preferred Label : Argatroban Anhydrous;

NCIt definition : The anhydrous form of argatroban, a synthetic derivative of L-arginine with antithrombotic activity. Argatroban is a univalent and direct inhibitor of fibrin-bound thrombin. This agent reversibly binds to the thrombin active site, thereby preventing the thrombin-dependent reactions, which include the conversion of fibrinogen to fibrin; the activation of factors V, VIII and XI; the activation of protein C; and platelet aggregation. Argatroban is highly selective for thrombin and is able to inhibit the action of both free and clot-associated thrombin. As a result, stabilization of blood clots occurs and coagulation is inhibited.;

UNII : OCY3U280Y3;

InChIKey : KXNPVXPOPUZYGB-IOVMHBDKSA-N;

CAS number : 74863-84-6;

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04/05/2025


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