Argatroban Anhydrous

Preferred Label : Argatroban Anhydrous;

NCIt definition : The anhydrous form of argatroban, a synthetic derivative of L-arginine with antithrombotic activity. Argatroban is a univalent and direct inhibitor of fibrin-bound thrombin. This agent reversibly binds to the thrombin active site, thereby preventing the thrombin-dependent reactions, which include the conversion of fibrinogen to fibrin; the activation of factors V, VIII and XI; the activation of protein C; and platelet aggregation. Argatroban is highly selective for thrombin and is able to inhibit the action of both free and clot-associated thrombin. As a result, stabilization of blood clots occurs and coagulation is inhibited.;

UNII : OCY3U280Y3;

InChIKey : KXNPVXPOPUZYGB-IOVMHBDKSA-N;

CAS number : 74863-84-6;

Details

Origin ID

C75153;

UMLS CUI

C2698183;

Automatic exact mappings (from CISMeF team)
- argatroban anhydrous [MeSH concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Argatroban anhydrous (substance) [SNOMED CT concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCIt COVID-19 Agent Terminology [NCIt concept]
- NCIt COVID-19 Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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