Acenocoumarol - CISMeF

Preferred Label : Acenocoumarol;

NCIt definition : A 4-hydroxycoumarin derivative with anticoagulant activity. As a vitamin K antagonist, acenocoumarol inhibits vitamin K epoxide reductase, thereby inhibiting the reduction of vitamin K and the availability of vitamin KH2. This prevents gamma carboxylation of glutamic acid residues near the N-terminals of the vitamin K-dependent clotting factors, including factor II, VII, IX, and X and anticoagulant proteins C and S. This prevents their activity and thus thrombin formation. Compared to other coumarin derivatives, acenocoumarol has a short half-life.;

UNII : I6WP63U32H;

InChIKey : VABCILAOYCMVPS-UHFFFAOYSA-N;

CAS number : 152-72-7;

Chemical formula : C19H15NO6;

ChEBI ID : CHEBI:53766;

Details

Origin ID

C75152;

UMLS CUI

C0000956;

Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Acenocoumarol [ICD-11 Extension code]
- Acenocoumarol [LOINC component]
- Acenocoumarol (substance) [SNOMED CT concept]
- Product containing acenocoumarol (medicinal product) [SNOMED CT concept]
- Sintrom [ICD-11 Extension code]
- acenocoumarol [ATC Code]
- acenocoumarol [Substance BNPC]
- acenocoumarol [MeSH Descriptor]
- acenocoumarol [MeSH concept]
- acenocoumarol [SNOMED Notion]
Validated automatic mappings to BTNT
- acenocoumarol [ATC Code]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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