" /> Topixantrone - CISMeF





Preferred Label : Topixantrone;

NCIt synonyms : Indazolo(4,3-gh)isoquinolin-6(2H)-one, 5-((2-(dimethylamino)ethyl)amino)-2-(2-((2-hydroxyethyl)amino)ethyl)-;

NCIt definition : A 9-aza-anthrapyrazole antineoplastic antibiotic. Topixantrone intercalates into DNA and interacts with topoisomerase II, thereby inhibiting DNA replication and repair as well as RNA and protein synthesis. Compared to other DNA intercalators, this agent shows minimal cardiotoxicity.;

UNII : R40RXC296C;

InChIKey : ZHAKYGFJVGCOAE-UHFFFAOYSA-N;

CAS number : 156090-18-5;

Molecule name : BBR 3576;

Chemical formula : C21H26N6O2;

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28/07/2025


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