Temocaprilat - CISMeF

Preferred Label : Temocaprilat;

NCIt definition : An angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity. Temocaprilat competitively binds to and inhibits ACE, thereby blocking the conversion of angiotensin I to angiotensin II. This prevents the potent vasoconstrictive actions of angiotensin II and results in vasodilation. Temocaprilat also decreases angiotensin II-induced aldosterone secretion by the adrenal cortex, which leads to an increase in sodium excretion and subsequently increases water outflow.;

UNII : 2D6A12Q12R;

InChIKey : KZVWEOXAPZXAFB-BQFCYCMXSA-N;

CAS number : 110221-53-9;

Chemical formula : C21H24N2O5S2;

Details

Origin ID

C75023;

UMLS CUI

C0646101;

Currated CISMeF NLP mapping
- temocaprilat [MeSH concept]
- temocaprilat [MeSH Supplementary Concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- temocaprilat [MeSH Supplementary Concept]
- temocaprilat [MeSH concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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