Preferred Label : Piperacillin Sodium;
NCIt synonyms : Sodium (2S,5R,6R)-6-((R)-2-(4-ethyl-2,3-dioxo-1-piperazinecarboxamido)-2-phenylacetamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylate; Piperacillin;
NCIt definition : The sodium salt of piperacillin, a broad-spectrum semisynthetic, ampicillin-derived
ureidopenicillin antibiotic with bactericidal activity. Piperacillin binds to and
inactivates penicillin-binding proteins (PBPs), enzymes located on the inner membrane
of the bacterial cell wall, resulting in the weakening of the bacterial cell wall
and cell lysis. PBPs participate in the terminal stages of assembling the bacterial
cell wall, and in reshaping the cell wall during cell division. Inactivation of PBPs
interferes with the cross-linkage of peptidoglycan chains necessary for bacterial
cell wall strength and rigidity.;
UNII : M98T69Q7HP;
InChIKey : WCMIIGXFCMNQDS-IDYPWDAWSA-M;
CAS number : 59703-84-3;
Drug name : Pipracil;
Molecule name : CL 227, 193; T-1220;
Chemical formula : C23H26N5O7S.Na;
ChEBI ID : CHEBI:8233;
Origin ID : C749;
UMLS CUI : C0700463;
Automatic exact mappings (from CISMeF team)
- See also inter- (CISMeF)
- Semantic type(s)
- Validated automatic mappings to NTBT
- concept_is_in_subset
- has_free_acid_or_base_form
- is_component_of_chemotherapy_regimen
- is_salt_form_of
