Anal Verrucous Carcinoma

Preferred Label : Anal Verrucous Carcinoma;

NCIt synonyms : Anal Buschke-Lowenstein Tumor; Anal Giant (Malignant) Condyloma;

NCIt definition : A large, well differentiated squamous cell carcinoma with a cauliflower-like appearance, characterized by the presence of an exophytic and endophytic growth pattern. Morphologically, there is papillomatosis and acanthosis present, however cytologically the neoplastic squamous cells have a benign appearance. Dysplastic changes are minimal. It does not respond to conservative treatment and it is regarded by many authors as an intermediate lesion between condyloma acuminatum and squamous cell carcinoma.;

Neoplastic status : Malignant;

Details

Origin ID

C7470;

UMLS CUI

C1332278;

Automatic exact mappings (from CISMeF team)
- anal Buschke-Lowenstein tumor [DO Concept]
DO Cross reference
- anal Buschke-Lowenstein tumor [DO Concept]
Disease excludes abnormal cell
- Malignant Stromal Cell [NCIt concept]
- Neoplastic Glandular Cell [NCIt concept]
- Neoplastic Smooth Muscle Cell [NCIt concept]
Excludes anatomical site(s)
- Extrahepatic Bile Duct [NCIt concept]
- Intrahepatic Bile Duct [NCIt concept]
Has associated anatomic sites
- Anus [NCIt concept]
- Digestive System [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
UMLS correspondences (same concept)
- anal Buschke-Lowenstein tumor [DO Concept]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
- Intermediate Grade Neuroendocrine Lesion [NCIt concept]
- Low Grade Neuroendocrine Lesion [NCIt concept]
- Mixed Neoplastic Glandular and Squamous Cell Population [NCIt concept]
- Mucoid Stroma Formation [NCIt concept]
- Pseudopapillary Pattern [NCIt concept]
- Well Differentiated Neuroendocrine Lesion [NCIt concept]
disease_has_abnormal_cell
- Malignant Cell [NCIt concept]
- Malignant Epithelial Cell [NCIt concept]
- Malignant Squamous Cell [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Epithelial Cell [NCIt concept]
- Neoplastic Squamous Cell [NCIt concept]
disease_has_finding
- Acanthosis [NCIt concept]
- Carcinomatous Component Present [NCIt concept]
- Endophytic Tumor Growth [NCIt concept]
- Epithelial Component Present [NCIt concept]
- Exophytic Papillary Lesion [NCIt concept]
- Hyperkeratosis [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
- Mild Cytologic Atypia [NCIt concept]
- Papillary Growth Pattern [NCIt concept]
- Pushing Tumor Margin [NCIt concept]
- Well Differentiated Lesion [NCIt concept]
disease_has_normal_cell_origin
- Epithelial Cell [NCIt concept]
disease_has_normal_tissue_origin
- Epithelial Tissue [NCIt concept]
disease_has_primary_anatomic_site
- Anus [NCIt concept]
- Digestive System [NCIt concept]
disease_may_have_molecular_abnormality
- MYC Gene Amplification [NCIt concept]
- TP53 Gene Inactivation [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients