Immunoglobulin Superfamily Member 8

Preferred Label : Immunoglobulin Superfamily Member 8;

NCIt synonyms : LIR-D1; CD81 Partner 3; CD316 Antigen; KCT-4; EWI-2; Keratinocytes-Associated Transmembrane Protein 4; Glu-Trp-Ile EWI Motif-Containing Protein 2; IGSF8;

NCIt definition : Immunoglobulin superfamily member 8 (613 aa, 65 kDa) is encoded by the human IGSF8 gene. This protein is involved in the regulation of cellular proliferation and motility.;

NCIt note : Immunoglobulin superfamily member 8 lays a role in Hepititis C infection by interacting with CD81 antigen.;

Details

Origin ID

C74516;

UMLS CUI

C1432340;

OMIM relation
- Immunoglobulin superfamily, member 8 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
UMLS correspondences (same concept)
- IGSF8 protein, human [MeSH Supplementary Concept]
- IGSF8 protein, human [MeSH concept]
gene_encodes_gene_product
- IGSF8 Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cellular Membrane [NCIt concept]
gene_product_has_chemical_classification
- Immunoglobulin Family Protein [NCIt concept]
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Immunoglobulin-Like C2-Type Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Motility [NCIt concept]
- Cell Proliferation [NCIt concept]
is_target
- Anti-IGSF8 Monoclonal Antibody GV20-0251 [NCIt concept]

Keyword's position in hierarchy(ies) :

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