NRP2 wt Allele

Preferred Label : NRP2 wt Allele;

NCIt synonyms : MGC126574; PRO2714; VEGF165R2; Neuropilin 2 wt Allele; NP2; NPN2; Receptor for VEGF165 and Semaphorins Class3 Gene;

NCIt definition : Human NRP2 wild-type allele is located in the vicinity of 2q33.3 and is approximately 116 kb in length. This allele, which encodes neuropilin-2 protein, is involved in the mediation of signal transduction associated with cardiovascular development, axon guidance, and tumorigenesis. Aberrant expression of the gene may contribute to colon cancer and autism.;

NCIt note : The NPR2 gene may both modulate metastasis of colon cancer cells and mediate the malignancy of pancreatic cancer. (Entrez Gene);

GenBank Accession Number : AF016098;

Details

Origin ID

C74469;

UMLS CUI

C2698422;

OMIM relation
- Neuropilin 2 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_is_element_in_pathway
- VEGFR1 Signaling Pathway [NCIt concept]
gene_plays_role_in_process
- Angiogenic Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Neural Development [NCIt concept]
- Organogenesis [NCIt concept]
- Receptor Signaling [NCIt concept]

Keyword's position in hierarchy(ies) :

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