" /> Elpamotide - CISMeF





Preferred Label : Elpamotide;

NCIt synonyms : VEGFR2-169; L-Arginyl-L-phenylalanyl-L-valyl-L-prolyl-L-alpha-aspartylglycyl-L-asparaginyl-L-arginyl-L-isoleucine Human Soluble (Vascular Endothelial Growth Factor Receptor) VEGFR2-(169-177)-peptide; VEGFR2-169 Peptide Vaccine;

NCIt definition : A peptide vaccine containing an HLA-A*2402-restricted epitope of vascular endothelial growth factor receptor (VEGFR) 2 with potential immunostimulatory and antineoplastic activities. Upon administration, VEGFR2-169 peptide vaccine may stimulate a cytotoxic T lymphocyte (CTL) response against VEGFR2-expressing tumor cells. VEGFR2, a receptor tyrosine kinase, is overexpressed by a variety of tumor types; overexpression is associated with tumor cell proliferation and tumor angiogenesis. HLA-A*2402 is an MHC class I molecule that presents antigenic peptides to CD8 T cells; epitope design restricted to epitopes that bind most efficiently to HLA-A*2402 may improve antigenic peptide immunogenicity.;

UNII : S68632MB2G;

InChIKey : ZAJHBCDPAUKEPU-GIKXZWSFSA-N;

CAS number : 673478-49-4;

NCI Metathesaurus CUI : CL383528;

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Keyword's position in hierarchy(ies) : arborescence

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10/05/2025


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