Preferred Label : URLC10-TTK-KOC1-VEGFR1-VEGFR2 Multipeptide Vaccine;
NCIt definition : A cancer vaccine containing five peptide epitopes with potential immunostimulatory
and antitumor activity. Peptide epitopes in this vaccine are derived from: URLC10
(up-regulated lung cancer 10), TTK (TTK protein kinase), KOC1 (IGF II mRNA Binding
Protein 3) and VEGFRs (vascular endothelial growth factor receptors) 1 and 2. Upon
administration, URLC10-TTK-KOC1-VEGFR1-VEGFR2 multipeptide vaccine may stimulate a
cytotoxic T lymphocyte (CTL) response against tumor cells expressing URLC10, TTK,
KCO1, VEGFR 1 and 2 peptides, resulting in cell lysis and decreased tumor growth.;
NCI Metathesaurus CUI : CL383869;
Origin ID : C74088;
UMLS CUI : C2348844;
Semantic type(s)
- chemical_or_drug_has_mechanism_of_action
- concept_is_in_subset
