Iodine I 131-6-Beta-Iodomethyl-19-Norcholesterol

Preferred Label : Iodine I 131-6-Beta-Iodomethyl-19-Norcholesterol;

NCIt synonyms : Radioiodine-Labeled Norcholesterol; I-131 NP-59;

NCIt definition : A radioiodine-labeled cholesterol analogue with radioisotopic activity. Iodine 131-I-6-beta-iodomethyl-19-norcholesterol accumulates in tissues where steroid hormones are produced, including the adrenal cortex and, to a lesser extent, the ovaries and the testes. After binding to low-density lipoprotein (LDL) receptors in the adrenal cortex, this agent is internalized, permitting scintigraphic localization of areas of adrenocortical glucocorticoid, mineralocorticoid and androgen secretion, and the scintigraphic assessment of adrenocortical function.;

Details

Origin ID

C74052;

UMLS CUI

C2346585;

Automatic exact mappings (from CISMeF team)
- I-131 NP59 [LOINC part]
- I-131 iodomethylnorcholesterol [Radlex concept]
- Iodine-131 iodocholesterol [Radlex concept]
Semantic type(s)
- Indicator, Reagent, or Diagnostic Aid [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
concept_is_in_subset
- NCI Drug Dictionary Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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