Preferred Label : Iodine I 125-Anti-EGFR-425 Monoclonal Antibody;
NCIt definition : A radioimmunoconjugate consisting of a murine IgG2a monoclonal antibody directed against
the human epidermal growth factor receptor (EGFR) labeled with iodine I 125 with potential
antineoplastic activity. Iodine I 125 anti-EGFR-425 monoclonal antibody binds specifically
to the epidermal growth factor receptor (EGFR). Upon binding to EGFR-expressing tumor
cells, this agent is internalized, selectively delivering a potentially cytotoxic
dose of gamma radiation. EGFR is a receptor tyrosine kinase that may be overexpressed
on the cell surfaces of various solid tumors.;
NCI Metathesaurus CUI : CL383810;
Origin ID : C74051;
UMLS CUI : C2346584;
Semantic type(s)
- concept_is_in_subset
