Preferred Label : Iodine I 124-Iodo-Azomycin Galactopyranoside;
NCIt synonyms : I-124 IAZGP;
NCIt definition : A diagnostic radiopharmaceutical comprised of iodo-azomycin galactopyranoside (IAZGP)
labeled with the positron-emitting radioisotope iodine I 124 and used as an imaging
agent. Iodine I 124 iodo-azomycin galactopyranoside (I-124 IAZGP) is reduced under
hypoxic conditions, covalently binding to macromolecules in hypoxic cells. After incorporation
into hypoxic tumor cell DNA, I-124 IAZGP can be localized and quantified using positron
emission tomography (PET), allowing a quantitative assessment of hypoxic tumor burden.
IAZGP appears to have a higher water solubility and faster clearance from normal tissue
than traditional imidazole tracers.;
NCI Metathesaurus CUI : CL383497;
Origin ID : C74050;
UMLS CUI : C2346583;
Semantic type(s)
- concept_is_in_subset
