Preferred Label : Indium In 111 Monoclonal Antibody HuPAM4;
NCIt synonyms : 111 In- Labeled Humanized PAM4 IgG; In-111-HuPAM4;
NCIt definition : The humanized monoclonal antibody huPAM4, directed against the pancreatic cancer antigen
MUC-1 and labeled with the gamma-emitting radioisotope indium In 111, with radioisotopic
and antibody activities. Upon administration, indium In 111 monoclonal antibody huPAM4
may bind to MUC-1-positive tumor cells, allowing radioimmunolocalization with gamma
scintigraphy. Overexpressed by many tumor cell types, MUC-1 antigen, a mammary-type
apomucin, is a high-molecular-weight transmembrane glycoprotein.;
NCI Metathesaurus CUI : CL383546;
Origin ID : C74048;
UMLS CUI : C2346491;
Semantic type(s)
- concept_is_in_subset
