Gallium Ga 68-DOTANOC

Preferred Label : Gallium Ga 68-DOTANOC;

NCIt definition : A gallium Ga 68-radiolabeled analogue of somatostatin that may be used in conjunction with positron emission tomography (PET) to image neuroendocrine tumors and metastases. Gallium Ga 68-DOTANOC is a conjugate of the somatostatin analogue Nal3-octreotide (NOC) and gallium Ga 68-labeled 1,4,7,10-tetraazacyclododecane-N,N',N'',N'''-tetraacetic acid (DOTA). The somatostatin analogue NOC has a high affinity for somatostatin receptor subtypes 2, 3, and 5; these receptor subtypes have been shown to be present in large numbers on neuroendocrine tumors and their metastases, while most other normal tissues express low levels of these somatostatin receptor subtypes.;

NCI Metathesaurus CUI : CL383790;

Details

Origin ID

C74034;

UMLS CUI

C3640098;

Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Indicator, Reagent, or Diagnostic Aid [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- gallium (68Ga) edotreotide [ATC Code]
concept_is_in_subset
- NCI Drug Dictionary Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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