Sovateltide - CISMeF

Preferred Label : Sovateltide;

NCIt synonyms : Endothelin B Receptor Agonist SPI-1620;

NCIt definition : A highly selective peptide agonist of the endothelin-B receptor. Sovateltide binds to endothelin-B receptors on endothelial cells in tumor blood vessels, which, unlike the angioarchitecture of normal blood vessels, are relatively devoid of smooth muscle. This agent may induce a transient, selective increase in blood flow to a tumor, which may result in an increase in the delivery of anticancer agents to the tumor and, so, an increase in anticancer agent efficacy.;

UNII : 11X778QIZS;

CAS number : 142569-99-1;

Molecule name : SPI-1620;

NCI Metathesaurus CUI : CL383531;

Details

Origin ID

C74027;

UMLS CUI

C5421242;

Currated CISMeF NLP mapping
- sovateltide [MeSH Supplementary Concept]
- sovateltide [MeSH concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- sovateltide [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
has_target
- Endothelin Receptor Type B [NCIt concept]

Keyword's position in hierarchy(ies) :

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