Aurora Kinase Inhibitor BI 811283

Preferred Label : Aurora Kinase Inhibitor BI 811283;

NCIt definition : A small molecule inhibitor of the serine/threonine protein kinase Aurora kinase with potential antineoplastic activity. Aurora kinase inhibitor BI 811283 binds to and inhibits Aurora kinases, resulting in disruption of the assembly of the mitotic spindle apparatus, disruption of chromosome segregation, and inhibition of cell proliferation.;

Molecule name : BI 811283;

NCI Metathesaurus CUI : CL383543;

Details

Origin ID

C74014;

UMLS CUI

C2346876;

Semantic type(s)
- Pharmacologic Substance [UMLS semantic type]
chemical_or_drug_affects_gene_product
- Aurora Kinase A [NCIt concept]
concept_is_in_subset
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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