" /> Otlertuzumab - CISMeF





Preferred Label : Otlertuzumab;

NCIt synonyms : Immunoglobulin, Anti-(Human CD Antigen CD37) (Synthetic Human-Mus Musculus Fragment TRU-016), Dimer; Anti-CD37 Single-Chain Polypeptide TRU-016;

NCIt definition : A recombinant single-chain polypeptide engineered to exhibit the full binding and activity of an anti-CD37 monoclonal antibody with potential immunostimulatory and antineoplastic activities. Otlertuzumab binds to CD37 on B-cells, which may result in antibody-dependent cell-mediated cytotoxicity (ADCC) and apoptosis. CD37 is a transmembrane glycoprotein expressed at high-levels on B cells and to a lesser extent on T cells and myeloid cells. This agent may have a longer half-life in vivo than conventional monoclonal antibodies.;

UNII : 2MZ3L2664T;

CAS number : 1372645-37-8;

Molecule name : TRU-016; TRU 016;

Codes from synonyms : 376;

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28/05/2025


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