" /> Fluciclovine F18 - CISMeF





Preferred Label : Fluciclovine F18;

NCIt synonyms : [18F]FACBC; Anti-1-Amino-3-[18F]Fluorocyclobutane-1-Carboxylic Acid; (1R,3R)-1-Amino-3(18f)fluorocyclobutane-1-carboxylic Acid; Anti-1-Amino-3-Fluorocyclobutane-1-Carboxylic Acid; 18F-Fluciclovine; Anti-[18F] FACBC; (18F)Fluciclovine; Fluciclovine (18F); Anti-(18f)FABC;

NCIt related terms : FLUCICLOVINE F-18; Axumin;

NCIt definition : A radiotracer containing a synthetic amino acid analogue of L-leucine radiolabeled with fluorine F 18 with potential diagnostic imaging use. Similar to most amino acids, fluciclovine F18 appears to enter cells through the energy-independent L-type amino acid transporter (LAT) system. As an amino acid analogue, this agent is preferentially accumulated by tumor cells due to their increased metabolic needs; however, unlike naturally occurring amino acids, this non-natural amino acid-analogue radiotracer is not metabolized. Accordingly, fluciclovine F18 accumulates in tumor cells and can potentially be used to image tumors using positron emission tomography (PET).;

UNII : 38R1Q0L1ZE;

InChIKey : NTEDWGYJNHZKQW-DGMDOPGDSA-N;

CAS number : 222727-39-1; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 222727-39-1 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Drug name : Axumin;

Molecule name : GE-148 F-18; (18F)GE-148;

Chemical formula : C5H8FNO2;

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15/05/2024


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