Preferred Label : Phenothiazine;
NCIt definition : A class of agents exhibiting antiemetic, antipsychotic, antihistaminic, and anticholinergic
activities. Phenothiazines antagonize the dopamine D2-receptor in the chemoreceptor
trigger zone (CTZ) of the brain, potentially preventing chemotherapy-induced emesis.
In addition, these agents have peripherally or centrally antagonistic activity against
alpha adrenergic, serotonergic, histaminic, and muscarinic receptors. (NCI);
Alternative definition : NCI-GLOSS: A type of drug that is used to treat severe mental and emotional disorders,
severe nausea and vomiting, and certain other conditions. It belongs to the families
of drugs called antipsychotics and antiemetics.;
UNII : GS9EX7QNU6;
InChIKey : WJFKNYWRSNBZNX-UHFFFAOYSA-N;
CAS number : 92-84-2;
Chemical formula : C12H9NS;
ChEBI ID : CHEBI:37931; CHEBI:38093;
Codes from synonyms : CDR0000467858; 04869;
Origin ID : C740;
UMLS CUI : C0031434;
See also inter- (CISMeF)
- Semantic type(s)
- UMLS correspondences (same concept)
- concept_is_in_subset
