Memantine - CISMeF

Preferred Label : Memantine;

NCIt definition : A low-affinity, voltage-dependent, noncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist. Memantine binds to and inhibits cation channels of glutamanergic NMDA receptors located in the central nervous system (CNS), preventing the prolonged influx of calcium ions and the associated neuronal excitotoxicity, and thereby potentially enhancing cognitive function. Memantine is also a 5-hydroxytryptamine type 3 (5HT3) receptor and nicotinic receptor antagonist.;

UNII : W8O17SJF3T;

InChIKey : BUGYDGFZZOZRHP-UHFFFAOYSA-N;

CAS number : 19982-08-2;

Chemical formula : C12H21N;

ChEBI ID : CHEBI:64312;

Details

Origin ID

C73269;

UMLS CUI

C0025242;

Currated CISMeF NLP mapping
- Memantine [LOINC component]
- Memantine [ICD-11 Extension code]
- Memantine [SMS substance]
- Memantine (substance) [SNOMED CT concept]
- memantine [Substance BNPC]
- memantine [MeSH Descriptor]
- memantine [MeSH concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Memantine [LOINC component]
- Memantine [ICD-11 Extension code]
- Memantine (substance) [SNOMED CT concept]
- Product containing memantine (medicinal product) [SNOMED CT concept]
- memantine [ATC Code]
- memantine [Substance BNPC]
- memantine [MeSH concept]
- memantine [MeSH Descriptor]
Validated automatic mappings to BTNT
- memantine [ATC Code]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
has_salt_form
- Memantine Hydrochloride [NCIt concept]
is_free_acid_or_base_form_of
- Memantine Hydrochloride [NCIt concept]

Keyword's position in hierarchy(ies) :

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