Erbulozole - CISMeF

Preferred Label : Erbulozole;

NCIt synonyms : Carbamic acid, (4-(((2-(1H-imidazol-1-ylmethyl)-2-(4-methoxyphenyl)-1,3-dioxolan-4-yl)methyl)thio)phenyl)-,ethyl ester, cis-( -)-;

NCIt definition : A water soluble congener of tubulozole and a tubulin binding agent with potential antimitotic and antineoplastic activities. Erbulozole targets and binds to tubulin, thereby preventing the polymerization of tubulin. This may lead to an inhibition of cell division and induction of apoptosis.;

UNII : 78XGN2K5RX;

InChIKey : KLEPCGBEXOCIGS-XUZZJYLKSA-N;

CAS number : 124784-31-2;

Molecule name : R55104;

Chemical formula : C24H27N3O5S;

Details

Origin ID

C73258;

UMLS CUI

C0059504;

Currated CISMeF NLP mapping
- erbulozole [MeSH concept]
- erbulozole [MeSH Supplementary Concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- erbulozole [MeSH concept]
- erbulozole [MeSH Supplementary Concept]
chemical_or_drug_has_mechanism_of_action
- Microtubule Process [NCIt concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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