Buciclovir - CISMeF

Preferred Label : Buciclovir;

NCIt synonyms : 2-Amino-9-(R)-3,4-dihydroxybutyl-9H-purin-6(1H)-on; (R)-9-(3,4-Dihydroxybutyl)guanine; BCV;

NCIt definition : An acyclic guanosine analog with activity against herpes simplex virus (HSV). Buciclovir is phosphorylated to its triphosphate form by HSV thymidine kinase in infected cells and acts as a specific inhibitor of the viral DNA polymerase. It is incorporated into both RNA and DNA but only inhibits DNA synthesis.;

UNII : 4G4Z4676IS;

InChIKey : QOVUZUCXPAZXDZ-RXMQYKEDSA-N;

CAS number : 86304-28-1;

Chemical formula : C9H13N5O3;

Details

Origin ID

C73198;

UMLS CUI

C0050178;

Currated CISMeF NLP mapping
- buciclovir [MeSH concept]
- buciclovir [MeSH Supplementary Concept]
Semantic type(s)
- Nucleic Acid, Nucleoside, or Nucleotide [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- buciclovir [MeSH concept]
- buciclovir [MeSH Supplementary Concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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