Etravirine - CISMeF

Preferred Label : Etravirine;

NCIt synonyms : 4-(6-Amino-5-bromo-2-(4-cyanoanilino)pyrimidin-4-yloxy)-3,5-dimethylbenzonitrile; ETV;

NCIt definition : A diarylpyrimidine non-nucleoside reverse transcriptase inhibitor. Etravirine is designed to be active against HIV isolates with mutations that confer resistance to the two most commonly prescribed first-generation NNRTIs. It can bind the enzyme reverse transcriptase (RT) in multiple conformations, both for native and mutant RT, thereby blocking the enzymatic activity of RT.;

UNII : 0C50HW4FO1;

InChIKey : PYGWGZALEOIKDF-UHFFFAOYSA-N;

CAS number : 269055-15-4;

Drug name : Intelence;

Molecule name : TMC-125;

Chemical formula : C20H15BrN6O;

ChEBI ID : CHEBI:63589;

Details

Origin ID

C73195;

UMLS CUI

C1456409;

See also inter- (CISMeF)
- Product containing etravirine (medicinal product) [SNOMED CT concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Etravirine [LOINC component]
- Etravirine (substance) [SNOMED CT concept]
- Product containing etravirine (medicinal product) [SNOMED CT concept]
- etravirine [ATC Code]
- etravirine [MeSH concept]
- etravirine [MeSH Supplementary Concept]
Validated automatic mappings to BTNT
- etravirine [ATC Code]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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