" /> Dexlansoprazole - CISMeF





Preferred Label : Dexlansoprazole;

NCIt synonyms : ( )-2-((R)-{(3-methyl-4-(2,2,2-trifluoroethoxy)pyridin-2-yl)methyl}sulfinyl)-1H-benzimidazole;

NCIt definition : The R-isomer of lansoprazole and a substituted benzimidazole prodrug with selective and irreversible proton pump inhibitor activity. As a weak base, dexlansoprazole accumulates in the acidic environment of the secretory canaliculus of the gastric parietal cell where it is converted to an active sulfenamide form that binds to cysteine sulfhydryl groups on the luminal aspect of the proton pump hydrogen-potassium adenosine triphosphatase (H /K ATPase), thereby inhibiting the pump's activity and the parietal cell secretion of H ions into the gastric lumen, the final step in gastric acid production.;

UNII : UYE4T5I70X;

InChIKey : MJIHNNLFOKEZEW-RUZDIDTESA-N;

CAS number : 138530-94-6;

Drug name : Kapidex;

Molecule name : TAK-390MR; T-168390;

Chemical formula : C16H14F3N3O2S;

Details


Keyword's position in hierarchy(ies) : arborescence

You can consult :


Nous contacter.
08/05/2025


[Home] [Top]

© Rouen University Hospital. Any partial or total use of this material must mention the source.