Emivirine - CISMeF

Preferred Label : Emivirine;

NCIt synonyms : MKC-442; EMV; 6-benzyl-1-(ethoxymethyl)-5-isopropyl-uracil;

NCIt definition : A non-nucleoside reverse transcriptase inhibitor. Emivirine has a structure typical of a nucleoside analog but has been shown to bind directly to the reverse transcriptase and act as an NNRTI. However, it is no longer in development due to the fact that it causes an increasingly rapid breakdown of other drugs metabolized by the cytochrome P450 enzyme.;

UNII : X87G8IX72O;

InChIKey : MLILORUFDVLTSP-UHFFFAOYSA-N;

CAS number : 149950-60-7;

Drug name : Coactinon;

Chemical formula : C17H22N2O3;

ChEBI ID : CHEBI:44143;

Details

Origin ID

C73147;

UMLS CUI

C0248121;

Automatic exact mappings (from CISMeF team)
- MKC 442 [MeSH concept]
Currated CISMeF NLP mapping
- emivirine [MeSH concept]
- emivirine [MeSH Supplementary Concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- emivirine [MeSH Supplementary Concept]
- emivirine [MeSH concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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