Splenic Manifestation of Hairy Cell Leukemia

Preferred Label : Splenic Manifestation of Hairy Cell Leukemia;

NCIt definition : Infiltration and expansion of the red pulp of the spleen by hairy cell leukemia.;

Neoplastic status : Malignant;

Details

Origin ID

C7301;

UMLS CUI

C1336064;

Automatic exact mappings (from CISMeF team)
- Classic hairy cell leukemia [ORDO Disease]
- leukemia, hairy cell [MeSH Descriptor]
- splenic manifestation of hairy cell leukemia [DO Concept]
DO Cross reference
- splenic manifestation of hairy cell leukemia [DO Concept]
Disease excludes abnormal cell
- Leukemic Plasma Cell [NCIt concept]
- Neoplastic T-Lymphocyte and Neoplastic Natural Killer Cell [NCIt concept]
Disease excludes normal cell origin
- Myeloid Cell [NCIt concept]
- Precursor B-Lymphoblast [NCIt concept]
Has associated anatomic sites
- Hematopoietic and Lymphatic System [NCIt concept]
- Spleen [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
disease_excludes_finding
- Acute Clinical Course [NCIt concept]
- Benign Cellular Infiltrate [NCIt concept]
- Solid Growth Pattern [NCIt concept]
disease_has_abnormal_cell
- Abnormal Lymphocyte [NCIt concept]
- Hairy Cell [NCIt concept]
- Leukemic Cell [NCIt concept]
- Leukemic Lymphocyte [NCIt concept]
- Malignant Cell [NCIt concept]
- Neoplastic B-Lymphocyte [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Hematopoietic and Lymphoid Cell [NCIt concept]
- Neoplastic Lymphocyte [NCIt concept]
disease_has_finding
- BRAF V600E Mutation Present [NCIt concept]
- Fried-Egg Appearance of the Bone Marrow [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
- Reticulin Fibrosis of the Bone Marrow [NCIt concept]
- Splenomegaly [NCIt concept]
- Tartrate Resistant Acid Phosphatase Positive Cells Present [NCIt concept]
disease_has_molecular_abnormality
- Clonal Immunoglobulin Gene Rearrangement [NCIt concept]
- Clonal Immunoglobulin Heavy Chain Gene Rearrangement [NCIt concept]
- Clonal Immunoglobulin Kappa Light Chain Gene Rearrangement [NCIt concept]
- Clonal Immunoglobulin Lambda Light Chain Gene Rearrangement [NCIt concept]
disease_has_normal_cell_origin
- B-Lymphocyte [NCIt concept]
- Hematopoietic and Lymphoid Cell [NCIt concept]
- Lymphocyte [NCIt concept]
- Mature B-Lymphocyte [NCIt concept]
- Postgerminal Center B-Lymphocyte of Unknown Differentiation Stage [NCIt concept]
disease_has_normal_tissue_origin
- Hematopoietic and Lymphoid Tissue [NCIt concept]
- Lymphoid Tissue [NCIt concept]
disease_has_primary_anatomic_site
- Bone Marrow [NCIt concept]
- Hematopoietic and Lymphatic System [NCIt concept]
- Lymphatic System [NCIt concept]
disease_mapped_to_gene
- BRAF Gene [NCIt concept]
disease_may_have_associated_disease
- Opportunistic Infection [NCIt concept]
- Vasculitis [NCIt concept]
disease_may_have_molecular_abnormality
- CCND1 Protein Overexpression [NCIt concept]

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