NCIt definition : The potassium salt of penicillin V, a member of the penicillin antibiotic family with
broad-spectrum bactericidal activity. Penicillin V binds to and inactivates penicillin-binding
proteins (PBPs), enzymes located on the inner membrane of the bacterial cell wall,
resulting in the weakening of the bacterial cell wall and cell lysis. PBPs participate
in the terminal stages of assembling the bacterial cell wall, and in reshaping the
cell wall during cell division. Inactivation of PBPs interferes with the cross-linkage
of peptidoglycan chains necessary for bacterial cell wall strength and rigidity.;