Splenic Manifestation of T-Cell Prolymphocytic Leukemia

Preferred Label : Splenic Manifestation of T-Cell Prolymphocytic Leukemia;

NCIt definition : Infiltration and expansion of the white and red pulp of the spleen by T-cell prolymphocytic leukemia.;

Neoplastic status : Malignant;

Details

Origin ID

C7298;

UMLS CUI

C1336068;

Disease excludes abnormal cell
- Leukemic Plasma Cell [NCIt concept]
- Neoplastic B-Lymphocyte [NCIt concept]
Disease excludes normal cell origin
- Myeloid Cell [NCIt concept]
- Precursor Natural Killer Cell [NCIt concept]
- Precursor T-Lymphoblast [NCIt concept]
Disease may have findings
- Aggressive Clinical Course [NCIt concept]
- Cutaneous Involvement [NCIt concept]
- Cytoplasmic Protrusions Present [NCIt concept]
- Effusion [NCIt concept]
- Hepatomegaly [NCIt concept]
- Lymphadenopathy [NCIt concept]
- Thrombocytopenia [NCIt concept]
- Unfavorable Clinical Outcome [NCIt concept]
Has associated anatomic sites
- Hematopoietic and Lymphatic System [NCIt concept]
- Spleen [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
disease_excludes_finding
- Acute Clinical Course [NCIt concept]
- Benign Cellular Infiltrate [NCIt concept]
- Solid Growth Pattern [NCIt concept]
disease_has_abnormal_cell
- Abnormal Lymphocyte [NCIt concept]
- Leukemic Cell [NCIt concept]
- Leukemic Lymphocyte [NCIt concept]
- Malignant Cell [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Hematopoietic and Lymphoid Cell [NCIt concept]
- Neoplastic Lymphocyte [NCIt concept]
- Neoplastic Prolymphocyte [NCIt concept]
- Neoplastic T-Lymphocyte and Neoplastic Natural Killer Cell [NCIt concept]
- Neoplastic T-Prolymphocyte [NCIt concept]
disease_has_finding
- Malignant Cellular Infiltrate [NCIt concept]
- Splenomegaly [NCIt concept]
disease_has_molecular_abnormality
- Clonal T-Cell Receptor Beta Chain Gene Rearrangement [NCIt concept]
- Clonal T-Cell Receptor Gamma Chain Gene Rearrangement [NCIt concept]
disease_has_normal_cell_origin
- Hematopoietic and Lymphoid Cell [NCIt concept]
- Lymphocyte [NCIt concept]
- Mature Lymphocyte [NCIt concept]
- Peripheral (Post-Thymic) T-Lymphocyte and Natural Killer Cell [NCIt concept]
- T-Lymphocyte and Natural Killer Cell [NCIt concept]
- T-Lymphocyte with a Post-Thymic Immunophenotype [NCIt concept]
disease_has_normal_tissue_origin
- Hematopoietic and Lymphoid Tissue [NCIt concept]
- Lymphoid Tissue [NCIt concept]
disease_has_primary_anatomic_site
- Bone Marrow [NCIt concept]
- Hematopoietic and Lymphatic System [NCIt concept]
- Lymphatic System [NCIt concept]
disease_may_have_associated_disease
- Anemia [NCIt concept]
disease_may_have_cytogenetic_abnormality
- Trisomy 8q [NCIt concept]
- del(12p13) [NCIt concept]
- inv(14) [NCIt concept]
- t(14;14)(q11;q32) [NCIt concept]
- t(8;8)(p11-12;q12) [NCIt concept]
- t(X;14)(q28;q11) [NCIt concept]

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