Preferred Label : Utibaprilat;
NCIt definition : A thiadiazoline angiotensin-converting enzyme (ACE) inhibitor with antihypertensive
activity. Utibaprilat competitively binds to and inhibits ACE, thereby blocking the
conversion of angiotensin I to angiotensin II. This prevents the potent vasoconstrictive
actions of angiotensin II and results in vasodilation. Utibaprilat also decreases
angiotensin II-induced aldosterone secretion by the adrenal cortex, which leads to
an increase in sodium excretion and subsequently increases water outflow.;
UNII : KN82541NHV;
InChIKey : APWZQGVRPRWXQK-NOLJZWGESA-N;
CAS number : 109683-79-6;
Molecule name : FPL 63547;
Chemical formula : C20H27N3O5S;
Origin ID : C72914;
UMLS CUI : C2349084;
Semantic type(s)
- concept_is_in_subset
