NCIt definition : A dialkyl ether dicarboxylic acid with antihyperlipidemic activity. In animal models
gemcabene increased high density lipoprotein (HDL) cholesterol levels and increased
HDL particle size. Low-density lipoprotein cholesterol, trigylcerides, and apolipoprotein
C-III levels were decreased as well. In human test subjects, the HDL lowering effect
of gemcabene was only seen in patients with high ( 200 mg/dl) levels of triglycerides.;