Ambazone - CISMeF

Preferred Label : Ambazone;

NCIt synonyms : p-Benzoquinone Amidinohydrazone Thiosemicarbazone;

NCIt definition : An antiseptic agent with potential antibacterial and antileukemic activity. Although the exact mechanism of action remains to be fully elucidated, ambazone appears to interfere with the membrane-bound nucleotide system by increasing the intracellular concentration of cAMP in leukemia cells and macrophages, which potentially contributes to this agent's antineoplastic activity. Furthermore, this agent's affinity for various cellular targets, i.e. membranes, nucleic acids and proteins, may contribute to the overall antibacterial effect.;

UNII : BYK4592A3Q;

InChIKey : MLMFUKWWZIZRHX-UWRPRBHNSA-N;

CAS number : 6011-12-7; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 6011-12-7 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Drug name : Faringosept;

Chemical formula : C8H11N7S;

Details

Origin ID

C72627;

UMLS CUI

C0043983;

Currated CISMeF NLP mapping
- 1,4-benzoquinone guanylhydrazone thiosemicarbazone [MeSH concept]
- 1,4-benzoquinone guanylhydrazone thiosemicarbazone [MeSH Supplementary Concept]
- 1,4-benzoquinone guanylhydrazone thiosemicarbazone [Substance BNPC]
- Ambazone [ICD-11 Extension code]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- 1,4-benzoquinone guanylhydrazone thiosemicarbazone [Substance BNPC]
- 1,4-benzoquinone guanylhydrazone thiosemicarbazone [MeSH concept]
- 1,4-benzoquinone guanylhydrazone thiosemicarbazone [MeSH Supplementary Concept]
- Ambazone [ICD-11 Extension code]
- ambazone [ATC Code]
Validated automatic mappings to BTNT
- ambazone [ATC Code]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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