Preferred Label : Recombinant Oxytocin;
NCIt synonyms : Oxytocin; Therapeutic Oxytocin;
NCIt definition : A synthetic cyclic peptide form of the naturally occurring posterior pituitary hormone
oxytocin. Oxytocin binds to oxytocin receptors in the uterine myometrium, which triggers
the G-protein coupled receptor signal transduction cascade that causes increased intracellular
calcium concentrations. Increased calcium concentration levels activate myosin light
chain kinase which, in turn, induces the formation of the contractile protein actomyosin.
This stimulates uterine smooth muscle contractions. This agent also stimulates smooth
muscles in the mammary glands, thereby causing lactation.;
UNII : 1JQS135EYN;
CAS number : 50-56-6;
Drug name : Pitocin; Syntocinon;
Chemical formula : C43H66N12O12S2;
ChEBI ID : CHEBI:7872;
Origin ID : C724;
UMLS CUI : C1704206;
Semantic type(s)
- concept_is_in_subset
