ALK-Positive Large B-Cell Lymphoma

Preferred Label : ALK-Positive Large B-Cell Lymphoma;

NCIt synonyms : Diffuse Large B-Cell Lymphoma with Expression of Full-Length Anaplastic Lymphoma Kinase; Diffuse Large B-Cell Lymphoma with Expression of Full-Length ALK; ALK-DLBCL;

NCIt related terms : ALK positive large B-cell lymphoma;

NCIt definition : A usually aggressive large B-cell lymphoma characterized by the presence of monomorphic immunoblast-like neoplastic B-lymphocytes in a sinusoidal growth pattern. The neoplastic B-lymphocytes express the ALK kinase but they lack the 2;5 translocation.;

Neoplastic status : Malignant;

ICD-O code : 9737/3;

Details

Origin ID

C7225;

UMLS CUI

C1333294;

Automatic exact mappings (from CISMeF team)
- ALK positive large B-cell lymphoma [ICD-11 Extension code]
- ALK-positive large B-cell lymphoma [ORDO Disease]
- ALK-positive large B-cell lymphoma [ICD-11 Subcategory]
- Anaplastic lymphoma kinase positive large B-cell lymphoma (disorder) [SNOMED CT concept]
- Anaplastic lymphoma kinase positive large B-cell lymphoma (morphologic abnormality) [SNOMED CT concept]
Disease excludes abnormal cell
- Neoplastic T-Lymphocyte and Neoplastic Natural Killer Cell [NCIt concept]
- Reed-Sternberg Cell [NCIt concept]
Disease excludes normal cell origin
- Myeloid Cell [NCIt concept]
- Plasma Cell [NCIt concept]
- Precursor B-Lymphoblast [NCIt concept]
Disease may have findings
- Lymphadenopathy [NCIt concept]
Has associated anatomic sites
- Hematopoietic and Lymphatic System [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
UMLS correspondences (same concept)
- Anaplastic lymphoma kinase positive large B-cell lymphoma (disorder) [SNOMED CT concept]
- Anaplastic lymphoma kinase positive large B-cell lymphoma (morphologic abnormality) [SNOMED CT concept]
concept_is_in_subset
- GDC Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- Mapped ICDO3.1 Morphology PT Terminology [NCIt concept]
- Mapped ICDO3.1 Morphology Terminology [NCIt concept]
- Mapped ICDO3.1 Terminology [NCIt concept]
- Mapped ICDO3.2 Morphology PT Terminology [NCIt concept]
- Mapped ICDO3.2 Morphology Terminology [NCIt concept]
- Mapped ICDO3.2 Terminology [NCIt concept]
- NCIt Neoplasm Core Terminology [NCIt concept]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
disease_has_abnormal_cell
- Abnormal Lymphocyte [NCIt concept]
- Malignant Cell [NCIt concept]
- Neoplastic B-Lymphocyte [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Hematopoietic and Lymphoid Cell [NCIt concept]
- Neoplastic Immunoblast-Like B-Lymphocyte [NCIt concept]
- Neoplastic Large B-Lymphocyte [NCIt concept]
- Neoplastic Lymphocyte [NCIt concept]
disease_has_finding
- Aggressive Clinical Course [NCIt concept]
- Diffuse Pattern [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
- Sinusoidal Growth Pattern [NCIt concept]
disease_has_molecular_abnormality
- ALK Kinase Overexpression [NCIt concept]
- Clonal Immunoglobulin Gene Rearrangement [NCIt concept]
- Clonal Immunoglobulin Kappa Light Chain Gene Rearrangement [NCIt concept]
disease_has_normal_cell_origin
- B-Lymphocyte [NCIt concept]
- Hematopoietic and Lymphoid Cell [NCIt concept]
- Lymphocyte [NCIt concept]
- Mature B-Lymphocyte [NCIt concept]
disease_has_normal_tissue_origin
- Hematopoietic and Lymphoid Tissue [NCIt concept]
- Lymphoid Tissue [NCIt concept]
disease_has_primary_anatomic_site
- Hematopoietic and Lymphatic System [NCIt concept]
- Lymphatic System [NCIt concept]
disease_may_have_abnormal_cell
- Reed-Sternberg-Like Cell [NCIt concept]
disease_may_have_molecular_abnormality
- Clonal Immunoglobulin Heavy Chain Gene Rearrangement [NCIt concept]
- Clonal Immunoglobulin Lambda Light Chain Gene Rearrangement [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients