Methotrexate-Associated Lymphoproliferative Disorder

Preferred Label : Methotrexate-Associated Lymphoproliferative Disorder;

NCIt synonyms : Methotrexate-Related Lymphoproliferation; Methotrexate-Related Lymphoproliferative Disorder;

NCIt definition : A lymphoproliferative disorder that develops in patients who are immunosuppressed with methotrexate. This disorder is often Epstein-Barr virus positive, and morphologically it may resemble large B-cell non-Hodgkin lymphoma, Hodgkin lymphoma, or a polymorphous post-transplant lymphoproliferative disorder. (WHO, 2001);

Neoplastic status : Malignant;

Details

Origin ID

C7184;

UMLS CUI

C1334749;

Automatic exact mappings (from CISMeF team)
- Lymphoproliferative disorder caused by methotrexate (disorder) [SNOMED CT concept]
- Methotrexate-associated lymphoproliferative disorders [ICD-11 More detail]
- methotrexate-associated lymphoproliferation [DO Concept]
Currated CISMeF NLP mapping
- Methotrexate-associated lymphoproliferative disorders [ORDO Disease]
DO Cross reference
- methotrexate-associated lymphoproliferation [DO Concept]
Disease excludes normal cell origin
- Myeloid Cell [NCIt concept]
Disease may have findings
- Extranodal Disease [NCIt concept]
- Lymphadenopathy [NCIt concept]
Has associated anatomic sites
- Hematopoietic and Lymphatic System [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
UMLS correspondences (same concept)
- Lymphoproliferative disorder caused by methotrexate (disorder) [SNOMED CT concept]
- Methotrexate-associated lymphoproliferative disorders [ORDO Disease]
- methotrexate-associated lymphoproliferation [DO Concept]
disease_excludes_finding
- Immunosuppression-Related Post-Transplant Toxicity [NCIt concept]
disease_has_abnormal_cell
- Abnormal Lymphocyte [NCIt concept]
disease_has_finding
- Immunodeficiency [NCIt concept]
- Therapy-Related Toxicity [NCIt concept]
disease_has_normal_cell_origin
- Hematopoietic and Lymphoid Cell [NCIt concept]
- Lymphocyte [NCIt concept]
disease_has_normal_tissue_origin
- Hematopoietic and Lymphoid Tissue [NCIt concept]
- Lymphoid Tissue [NCIt concept]
disease_has_primary_anatomic_site
- Hematopoietic and Lymphatic System [NCIt concept]
- Lymphatic System [NCIt concept]
disease_may_have_associated_disease
- EBV Infection [NCIt concept]

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