" /> Nifurtimox - CISMeF





Preferred Label : Nifurtimox;

NCIt definition : A nitrofuran derivative with antiprotozoal and potential antineoplastic activities. Nifurtimox is reduced by cytosol enzymes or flavin-containing microsomal enzymes to a highly reactive nitro anion free radical; autooxidation of the nitro anion free radical generates cytotoxic superoxide anion (02-). In addition, nifurtimox-derived nitro anion free radicals may alkylate macromolecules such as nucleic acids and proteins, resulting in the disruption of their structure and function.;

UNII : M84I3K7C2O;

InChIKey : ARFHIAQFJWUCFH-IZZDOVSWSA-N;

CAS number : 23256-30-6;

Drug name : Lampit;

Molecule name : 4-((5-Nitrofurfurylidene)amino)-3-methylthiomorpholine-1,1-dioxide; BAY 2502; BAYER 2502;

Chemical formula : C10H13N3O5S;

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28/07/2025


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