Preferred Label : Intranasal Ketamine;
NCIt definition : An intranasal formulation of the synthetic cyclohexanone ketamine with analgesic and
anesthetic activities. Although its mechanism of action is not well understood, ketamine
appears to non-competitively block N-methyl-D-aspartate (NMDA) receptors and agonistically
bind to and activate opioid mu and sigma receptors, thereby reducing pain perception,
inducing sedation, and producing dissociative anesthesia.;
NCI Metathesaurus CUI : CL376135;
Origin ID : C71709;
UMLS CUI : C2346514;
Semantic type(s)
- concept_is_in_subset
