Olivomycin - CISMeF

Preferred Label : Olivomycin;

NCIt synonyms : Olivomycins; Oligomycin A, mixt. with oligomycin B; Toyomycin R; Olivomycin Antibiotic;

NCIt definition : A preparation containing a mixture of glycosidic antibiotics isolated from Streptomyces olivoreticuli with fluorescent microscopy applications and potential antineoplastic activities. Olivomycin preferentially binds to DNA and can be utilized as a fluorescent marker during the characterization of heterochromatin. Additionally, binding to DNA inhibits both RNA transcription and RNA elongation by RNA polymerase; therefore protein synthesis is inhibited. In addition, olivomycin antibiotics are able to induce apoptosis in tumor cells through a mechanism that has not yet been fully elucidated.;

UNII : 44003517D1;

CAS number : 11006-70-5;

NSC code : 76411;

ChEBI ID : CHEBI:52515;

Codes from synonyms : NSC0076411;

Details

Origin ID

C715;

UMLS CUI

C0028967;

Automatic exact mappings (from CISMeF team)
- Olivomycin [ICHI extension code]
- olivomycin A [MeSH concept]
- olivomycin A [MeSH Supplementary Concept]
Currated CISMeF NLP mapping
- Olivomycin [ICD-11 Extension code]
- olivomycins [MeSH Descriptor]
- olivomycins [MeSH concept]
Semantic type(s)
- Antibiotic [UMLS semantic type]
- Indicator, Reagent, or Diagnostic Aid [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
UMLS correspondences (same concept)
- Olivomycin [ICD-11 Extension code]
- olivomycins [MeSH concept]
- olivomycins [MeSH Descriptor]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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