" /> PRNP wt Allele - CISMeF





Preferred Label : PRNP wt Allele;

NCIt synonyms : GSS; Prion Protein (p27-30) (Creutzfeldt-Jakob Disease, Gerstmann-Strausler-Scheinker Syndrome, Fatal Familial Insomnia) wt Allele; PrP27-30; ASCR; MGC26679; PrPc; PRIP; CJD; PrP; CD230; PrP33-35C;

NCIt definition : Human PRNP wild-type allele is located in the vicinity of 20p13 and is approximately 15 kb in length. This allele, which encodes major prion protein, plays a role in both the extracellular surface and the development of prion diseases. Mutations in the gene are associated with inherited transmissible spongiform encephalopathies.;

NCIt note : The PRNP gene product may be a factor in the pathology and transmission of Creutzfeldt-Jakob disease (CJD), fatal familial insomnia (FFI), Gerstmann-Straussler disease (GSD), Huntington disease-like 1 (HDL1) and kuru in humans.;

GenBank Accession Number : M13899;

Details


Keyword's position in hierarchy(ies) : arborescence

You can consult :


Nous contacter.
29/05/2025


[Home] [Top]

© Rouen University Hospital. Any partial or total use of this material must mention the source.