PLAG1 wt Allele

Preferred Label : PLAG1 wt Allele;

NCIt synonyms : PSA; SGPA; Pleiomorphic Adenoma Gene 1 Gene; PLAG1 Zinc Finger wt Allele; SRS4; ZNF912;

NCIt definition : Human PLAG1 wild-type allele is located in the vicinity of 8q12 and is approximately 50 kb in length. This allele, which encodes zinc finger protein PLAG1, plays a role in cellular proliferation. Mutation or translocation of this gene is associated with hepatoblastoma, lipoblastoma and salivary gland pleiomorphic adenomas.;

NCIt note : Pathological translocations involving the PLAG1 gene include t(3;8)(p21;q12), which fuses this gene to the CTNNB1 gene, and t(7;8)(p22;q13), which fuses PLAG1 to the COL1A2 gene. (SwissProt);

GenBank Accession Number : U65002;

Détails

Origin ID

C71424;

UMLS CUI

C2347427;

Automatic exact mappings (from CISMeF team)
- Aminopeptidase, puromycin-sensitive [OMIM gene]
- Kallikrein-related peptidase 3 [OMIM gene]
- PLAG1 zinc finger [ORDO Gene]
- PSA [MedDRA LLT]
- Prostate specific antigen positive [ICD-11 Sub-sub category]
- Prostate-Specific antigen [MeSH Descriptor]
- Prostatic specific antigen [MedDRA Preferred Term]
- Protein s [OMIM gene]
- Silver-russell syndrome 4 [OMIM Phenotype]
- Streptogrisin A (substance) [SNOMED CT concept]
- periaqueductal gray [MeSH Descriptor]
- phosphoserine aminotransferase 1 [ORDO Gene]
- polysialic acid [MeSH Supplementary Concept]
False automatic mappings
- Salivary gland adenoma, pleomorphic [OMIM Phenotype]
OMIM relation
- Plag1 zinc finger protein [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_involved_in_pathogenesis_of_disease
- Salivary Gland Pleomorphic Adenoma [NCIt concept]
gene_plays_role_in_process
- DNA Binding [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Position du mot-clé dans l'(les) arborescence(s) :

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