HLA-DPA1 wt Allele

Preferred Label : HLA-DPA1 wt Allele;

NCIt synonyms : HLASB; HLADP; DASS-32K24.2; HLA DP1A; Major Histocompatibility Complex, Class II, DP Alpha 1 wt Allele;

NCIt definition : Human HLA-DPA1 wild-type allele is located in the vicinity of 6p21.3 and is approximately 16 kb in length. This allele, which encodes HLA class II histocompatibility antigen, DP alpha chain protein, is involved in the modulation of antigen presentation and T-cell mediated immunity. The gene is polymorphic and typing is often performed to determine histocompatibility for hematopoietic stem cell transplantation.;

NCIt note : The HLA-DPA1 gene is expressed as multiple isoforms that dimerize with HLA-DP beta chain proteins to form the HLA-DP complex.;

GenBank Accession Number : X00457;

Details

Origin ID

C71268;

UMLS CUI

C2348921;

Automatic exact mappings (from CISMeF team)
- HLA-DP [LOINC component]
- HLA-DP antigens [MeSH Descriptor]
- Major histocompatibility complex, class II, dp alpha-1 [OMIM gene]
OMIM relation
- Major histocompatibility complex, class II, dp alpha-1 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 6p21.3 [NCIt concept]
gene_plays_role_in_process
- Antigen Presentation [NCIt concept]
- Immune System Process [NCIt concept]
- Immunoregulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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