" /> HLA-DRB3 wt Allele - CISMeF





Preferred Label : HLA-DRB3 wt Allele;

NCIt synonyms : HLA-DR3B; Major Histocompatibility Complex, Class II, DR Beta 3 wt Allele; MGC117330; Human Leucocyte Antigen DRB3; Human Leukocyte Antigen DRB3;

NCIt definition : Human HLA-DRB3 wild-type allele is located in the vicinity of 6p21.3 and is approximately 13 kb in length. This allele, which encodes HLA class II histocompatibility antigen, DRB3 beta chain protein, is involved in the mediation of antigen presentation and stimulation of the immune response. The gene is polymorphic and typing is often performed to determine histocompatibility for hematopoietic stem cell transplantation.;

NCIt note : The HLA-DRB3 gene is expressed as multiple isoforms that determine the HLA-DR52 antigen serotype. The gene product is a beta subunit for the HLA-DR complex.;

GenBank Accession Number : BC008987;

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04/05/2025


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