Preferred Label : Natural IFN-alpha OPC-18;
NCIt synonyms : nIFN-alpha OPC-18;
NCIt definition : A proprietary preparation of natural human interferon alpha (IFN alpha) with potential
immunomodulatory and antineoplastic activities. Natural human interferon alpha OPC-18
binds to cell-surface IFN alpha receptors (IFNARs), resulting in the transcription
and translation of genes whose products mediate antiviral, antiproliferative, and
immune-modulating effects. IFN alpha is a type I interferon produced by peripheral
blood leukocytes or lymphoblastoid cells when exposed to live or inactivated virus,
double-stranded RNA, or bacterial products and is the primary interferon produced
by virus-induced leukocyte cultures. In addition to its pronounced antiviral activity,
it activates NK cells.;
Molecule name : OPC-18;
NCI Metathesaurus CUI : CL376209;
Origin ID : C71159;
UMLS CUI : C2347330;
Semantic type(s)
- concept_is_in_subset
