Preferred Label : Autologous Follicular Lymphoma-Derived Idiotype Vaccine;
NCIt definition : A patient-specific cancer vaccine directed against the soluble protein idiotype of
an individual follicular lymphoma with potential antineoplastic activity. A patient-specific
follicular lymphoma-derived anti-idiotype vaccine may be composed of a patient-specific,
synthetic idiotype-related peptide (such as one corresponding to a hypervariable region
of an IgG heavy chain) conjugated to the immunostimulant carrier protein keyhole limpet
hemocyanin (KLH). Upon administration, this vaccine may induce an idiotype-specific
cytotoxic T-lymphocyte (CTL) response against follicular lymphoma cells expressing
the idiotype, resulting in tumor cell lysis.;
Origin ID : C71036;
UMLS CUI : C2346884;
Semantic type(s)
- concept_is_in_subset
