NCIt related terms : Nadofaragene Firadenovec/Syn3;
NCIt definition : A replication-deficient recombinant adenovirus encoding human interferon alpha-2b
with potential antineoplastic activity. Upon intravesical administration, nadofaragene
firadenovec infects nearby tumor cells and expresses INF alpha-2b intracellularly
which activates the transcription and translation of genes whose products mediate
antiviral, antiproliferative, antitumor, and immune-modulating effects.;