Tyrosine Kinase Inhibitor OSI-930

Preferred Label : Tyrosine Kinase Inhibitor OSI-930;

NCIt related terms : OSI-930;

NCIt definition : A selective thiophene-derived tyrosine kinase inhibitor with potential antineoplastic activity. Tyrosine kinase inhibitor OSI-930 inhibits stem cell factor receptor (c-Kit) and the vascular endothelial growth factor receptor 2 (VEGFR2), which may result in the inhibition of both tumor cell proliferation and tumor angiogenesis. Both c-Kit and VEGFR2 are overexpressed in a variety of cancers.;

UNII : G1PEG5Q9Y2;

CAS number : 728033-96-3; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 728033-96-3 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Molecule name : OSI-930;

Details

Origin ID

C70981;

UMLS CUI

C1615605;

Automatic exact mappings (from CISMeF team)
- OSI 930 [MeSH concept]
- OSI 930 [MeSH Supplementary Concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- OSI 930 [MeSH Supplementary Concept]
- OSI 930 [MeSH concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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