Preferred Label : Mycobacterium w;
NCIt related terms : MYCOBACTERIUM INDICUS PRANII;
NCIt definition : An attenuated strain of Mycobacterium w, a non-pathogenic, rapidly growing, atypical
mycobacterium, with non-specific immunopotentiating properties. In addition to sharing
a number of common B and T cell determinants with Mycobacterium leprae and Mycobacterium
tuberculosis, Mycobacterium w (Mw) also shares an immunogenic determinant with prostate
specific antigen (PSA). In vitro and in vivo studies have shown that heat-killed Mw
can induce significant T-cell responses. This agent may induce host T-cell responses
against tumor cells expressing PSA. PSA is a glycoprotein secreted by prostatic epithelial
and ductal cells and may be overexpressed in prostate cancer cells.;
UNII : 8R0TB70HKB;
Drug name : Immuvac;
NCI Metathesaurus CUI : CL375836;
Origin ID : C70969;
UMLS CUI : C2349988;
Automatic exact mappings (from CISMeF team)
- Semantic type(s)
- concept_is_in_subset
