Preferred Label : Gadobutrol;
NCIt synonyms : (10-((1RS,2SR)-2,3-Dihydroxy-1-(hydroxymethyl)propyl)-1,4,7,10-tetraazacyclododecane-1,4,7-triacetato(3-))gadolinium;
NCIt definition : A gadolinium-based, hydrophilic, macrocyclic, electrically neutral contrast agent
used in contrast-enhanced MRI (CE-MRI). Gadobutrol is a non-ionic, paramagnetic complex
consisting of gadolinium (Gd3 ) chelated with the macrocyclic compound dihydroxy-hydroxymethylpropyl-tetraazacyclododecane-triacetic
acid (butrol). Following intravenous administration, gadobutrol may increase MRI sensitivity
for the detection of tumors and inflammatory and demyelinating diseases of the central
nervous system (CNS) that are associated with areas with blood-brain barrier defects
due to altered perfusion or an enlarged extracellular space. This agent is eliminated
in an unchanged form via the kidneys; extra-renal elimination is negligible.;
UNII : 1BJ477IO2L;
InChIKey : ZPDFIIGFYAHNSK-CTHHTMFSSA-K;
CAS number : 138071-82-6;
Drug name : Protovis; Gadograf; Gadovist; Gadavist;
Molecule name : BAY86-4875; ZK 135079;
Chemical formula : C18H31N4O9.Gd;
Origin ID : C70675;
UMLS CUI : C0291216;
See also inter- (CISMeF)
- Semantic type(s)
- UMLS correspondences (same concept)
- Validated automatic mappings to BTNT
- concept_is_in_subset
