Preferred Label : Plant-Derived Hematopoiesis Enhancer PG2;
NCIt definition : A proprietary botanical formulation derived from a traditional Chinese medicinal (TCM)
plant with hematopoietic activity. Although the mechanism of action has yet to be
fully elucidated, plant-derived hematopoiesis enhancer PG2 appears to stimulate multi-lineage
progenitor cells that may be closely related to the hematopoietic stem cell. In both
chemotherapy- and radiation therapy-induced animal models of myelosuppression, this
agent has been shown to restore granulocyte, erythrocyte, and platelet counts to normal
levels. Plant-derived hematopoiesis enhancer PG2 stimulates the production of numerous
cytokines such as granulocyte-colony stimulating factor (G-CSF) and may stimulate
the production of neuroendocrine hormones.;
Molecule name : PG2;
NCI Metathesaurus CUI : CL375858;
Origin ID : C70640;
UMLS CUI : C2347529;
Semantic type(s)
- concept_is_in_subset
